Add to ORKGOBJECTIVE—Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabolic processes. We in-vestigate the site of resveratrol action on glucose metabolism and the contribution of SIRT1 to these effects. Because the arcuate nucleus in the mediobasal hypothalamus (MBH) plays a pivotal role in integrating peripheral metabolic responses to nutrients and hormones, we examined whether the actions of resveratrol are mediated at the MBH
The sirtuins are a family of highly evolutionary conserved NAD+-dependent deacetylases (SIRT1, 2, 3,...
Neurons in the dorsal motor nucleus of the vagus (DMV) play a critical role in the regulation of aut...
Growth hormone (GH) is a major anabolic hormone and the primary regulator of organism growth. Its tr...
OBJECTIVE—Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabo...
Oral resveratrol improves insulin sensitivity in obese or diabetic rodents, but the underlying mecha...
Oral resveratrol improves insulin sensitivity in obese or diabetic rodents, but the underlying mecha...
Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties ...
Sirtuins are energy sensors which mediate effects of calorie restriction-induced lifespan extension....
Central regulation of energy balance involves a coordination of several hormonal and nutritional inp...
The endocrine system plays an essential role in the physiological adaptation to malnutrition. The ad...
Amino acids profoundly affect insulin action and glucose me-tabolism in mammals. Here, we investigat...
Abstract Resveratrol is a natural polyphenolic compound that activates nicotinamide adenosine dinuc...
The hypothalamus is a small structure located in the ventral diencephalon. Hypothalamic neurons sens...
Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of proces...
International audienceMelanin-concentrating hormone (MCH) is an important regulator of food intake, ...
The sirtuins are a family of highly evolutionary conserved NAD+-dependent deacetylases (SIRT1, 2, 3,...
Neurons in the dorsal motor nucleus of the vagus (DMV) play a critical role in the regulation of aut...
Growth hormone (GH) is a major anabolic hormone and the primary regulator of organism growth. Its tr...
OBJECTIVE—Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabo...
Oral resveratrol improves insulin sensitivity in obese or diabetic rodents, but the underlying mecha...
Oral resveratrol improves insulin sensitivity in obese or diabetic rodents, but the underlying mecha...
Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties ...
Sirtuins are energy sensors which mediate effects of calorie restriction-induced lifespan extension....
Central regulation of energy balance involves a coordination of several hormonal and nutritional inp...
The endocrine system plays an essential role in the physiological adaptation to malnutrition. The ad...
Amino acids profoundly affect insulin action and glucose me-tabolism in mammals. Here, we investigat...
Abstract Resveratrol is a natural polyphenolic compound that activates nicotinamide adenosine dinuc...
The hypothalamus is a small structure located in the ventral diencephalon. Hypothalamic neurons sens...
Sirt1 is an evolutionarily conserved NAD(+) dependent deacetylase involved in a wide range of proces...
International audienceMelanin-concentrating hormone (MCH) is an important regulator of food intake, ...
The sirtuins are a family of highly evolutionary conserved NAD+-dependent deacetylases (SIRT1, 2, 3,...
Neurons in the dorsal motor nucleus of the vagus (DMV) play a critical role in the regulation of aut...
Growth hormone (GH) is a major anabolic hormone and the primary regulator of organism growth. Its tr...