org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Efficacy of Long-Term Daily Dosage of Alfuzosin 10 mg upon Sexual Function of Benign Prostat

Purpose: To identify sexual function improvement associated with alfuzosin (10 mg daily for 2 years). Materials and Methods: We enrolled 30 men with lower urinary tract symptom (LUTS) who visited Gyeongsang National University Hospital between 2010 and 2012. At first visit, urinalysis, prostate specific antigen, transrectal ultrasound, and uroflowmetry were performed. The nternational Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF), and Male Sexual Health Questionnaire Ejaculation Function Domain (MSHQ-EjFD) questionnaires were administered, and the subjects answered the same questionnaires at 1 month, 6 months, 1 year, and 2 years of follow-up. Results: Twelve men completed of the entire study. After administration of alfuzosin, the median IPSS at first visit, 1 month, 6 months, 1 year, and 2 years was 18.00 (interquatile range [IQR]: 14.00∼29.75), 20.00 (IQR: 11.50∼30.00), 15.50 (IQR: 8.50∼ 25.25), 14.50 (IQR: 9.25∼19.50), and 11.50 (IQR: 5.00∼17.75), respectively, which showed an improvement. The median QoL at the same times was 4.50 (IQR: 4.00∼5.00), 4.50 (IQR: 4.00∼5.00), 3.00 (IQR: 2.00∼4.00), 3.50 (IQR: 2.25∼4.00), and 3.0