Published Online First

Aim: Squamous differentiation in eccrine porocarcinoma (EPC) is an unusual phenomenon that has rarely been reported in the literature. This study describes the clinical and pathological findings in a series of 21 cases of EPC showing extensive squamous differentiation. Methods: The H&E-stained sections, epithelial membrane antigen and carcinoembryonic antigen immunohisto-chemical stains were reviewed for each case. The following variables were examined: age, gender, race, site and size of the EPC. The prevalence of other cutaneous lesions and/or underlying systemic disease was also documented. Results: There was an almost equal gender distribution. Mean age was 61.5 years and the average tumour siz