Complete genome sequence analysis of a duck circovirus from Guangxi pockmark ducks

We report here the complete genomic sequence of a novel duck circovirus (DuCV) strain, GX1104, isolated fromGuangxi pock-mark ducks in Guangxi, China. The whole nucleotide sequence had the highest homology (97.2%) with the sequence of strain TC/2002 (GenBank accession number AY394721.1) and had a low homology (76.8 % to 78.6%) with the sequences of other strains isolated from China, Germany, and the United States. This report will help to understand the epidemiology andmolecu-lar characteristics of Guangxi pockmark duck circovirus in southern China. Duck circovirus (DuCV), isolated fromMuscovy duck (3) andmulard duck (5), is involved in duck diseases, with the main clinical symptoms including immunosuppression and feather dis-orders in young ducks. The genome of DuCV is circular and 1,996 nucleotides (nt) in size. Two major open reading frames (ORFs) were identified, encoding the replicase (V1) and the capsid protein (C1) (4). DuCV was first reported in Germany (3) and was also recently reported in China (1, 2, 6). The whole nucleotide se-quences of these strains had a homology of 83.2 % to 99.8%. In April 2011, DuCV was isolated from a commercial Guangxi pockmark duck farm with an outbreak of an infectious diseas