Add to ORKGTo elucidate the genetic factors predisposing to AIDS progression, we analyzed a unique cohort of 275 human immunodeficiency virus (HIV) type 1–seropositive nonprogressor patients in relation to a control group of 1352 seronegative individuals in a genomewide association study (GWAS). The strongest association was obtained for HCP5 rs2395029 (P 6.79 1010; odds ratio, 3.47) andwaspossibly linked toaneffectof sex. Interestingly, this single-nucleotide polymorphism (SNP) was in high linkage disequilibriumwith HLA-B, MICB, TNF, and several other HLA locus SNPs and haplotypes. A meta-analysis of our genomic data combined with data from the previ
International audienceBackgroundPrevious genomewide association studies (GWASs) of AIDS have targete...
Previous genome-wide association studies (GWAS) of HIV-1–infected populations have been underpowered...
We performed a genome-wide association study comparing a cohort of 144 human immunodeficiency virus ...
To elucidate the genetic factors predisposing to AIDS progression, we analyzed a unique cohort of 27...
A recent genome-wide association study (GWAS) suggested that polymorphisms in or around the genes HC...
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, i...
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, i...
International audiencePrevious studies of the HIV-1 disease have shown that HLA and Chemokine recept...
International audienceWe performed a genome-wide association study comparing a cohort of 144 human i...
Previous studies of the HIV-1 disease have shown that HLA and Chemokine receptor genetic variants in...
International audienceBackgroundPrevious genomewide association studies (GWASs) of AIDS have targete...
Previous genome-wide association studies (GWAS) of HIV-1–infected populations have been underpowered...
We performed a genome-wide association study comparing a cohort of 144 human immunodeficiency virus ...
To elucidate the genetic factors predisposing to AIDS progression, we analyzed a unique cohort of 27...
A recent genome-wide association study (GWAS) suggested that polymorphisms in or around the genes HC...
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, i...
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, i...
International audiencePrevious studies of the HIV-1 disease have shown that HLA and Chemokine recept...
International audienceWe performed a genome-wide association study comparing a cohort of 144 human i...
Previous studies of the HIV-1 disease have shown that HLA and Chemokine receptor genetic variants in...
International audienceBackgroundPrevious genomewide association studies (GWASs) of AIDS have targete...
Previous genome-wide association studies (GWAS) of HIV-1–infected populations have been underpowered...
We performed a genome-wide association study comparing a cohort of 144 human immunodeficiency virus ...