Estimation of thyroid hormone status and thyroid antibodies in type-1 diabetes mellitus

Autoimmune thyroid diseases are frequent in patients with type-1 diabetes mellitus. The aim of the study is to determine the incidence of autoimmune thyroid diseases (AIT) in type 1 diabetes mellitus patients which helps to provide early care and treatment. Thirty cases of type-1 diabetes mellitus were included. Serum TSH, serum FT3, serum FT4, anti Tg Ab, anti TPO levels were measured. A significant increase in the levels of anti Tg Ab, anti TPO and serum FT3 was observed. There was no significant difference in the levels of serum FT4 and serum TSH. These findings suggest that there is a strong association between type 1 DM and autoimmune thyroid disorders. The detection of these abnormalities in early stage will help the patients to improve quality of life and reduce the morbidity rate