Abstract: This study presents the results from detailed experiments of the two-phase pressurized flow behavior during the rapid filling of a large-scale pipeline. The physical scale of this experiment is close to the practical situation in many industrial plants. Pressure transducers, water-level meters, thermometers, void fraction meters, and flow meters were used to measure the two-phase unsteady flow dynamics. The main focus is on the water–air interface evolution during filling and the overall behavior of the lengthening water column. It is observed that the leading liquid front does not entirely fill the pipe cross section; flow stratification and mixing occurs. Although flow regime transition is a rather complex phenomenon, certain fe...