The filoviruses, Ebola and Marburg, are two of the most pathogenic viruses, causing lethal hemorrhagic fever in humans. Recent discoveries suggest that filoviruses, along with other phylogenetically or functionally related viruses, utilize a complex mechanism of replication exploiting multiple cellular components including lipid rafts, endocytic compartments, and vacuolar protein sorting machinery. In this review, we summarize these recent findings and discuss the implications for vaccine and therapeutics development. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved
Lloviu virus (LLOV), a novel filovirus detected in bats, is phylogenetically distinct from viruses i...
Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease charact...
Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable out...
Spatiotemporal aspects of filovirus entry and release are poorly understood. Lipid rafts act as func...
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The filoviruses Ebolavirus and Marburgviru...
The filoviruses Ebolavirus and Marburgvirus are among the deadliest viral pathogens known to infect ...
International audienceThere are no approved medications for the treatment of Marburg or Ebola virus ...
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Ear...
Since their discovery, the Ebola and Marburg virus cause regular outbreaks with lethality in humans ...
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in humans f...
International audienceFiloviruses are important pathogens that cause severe and often fatal hemorrha...
Filoviruses cause severe hemorrhagic fever in humans with high case-fatality rates. The cellular fac...
Lipid-enveloped viruses contain a lipid bilayer coat that protects their genome and helps to facilit...
Abstract: Ebola- and marburgviruses are highly pathogenic filoviruses and causative agents of viral ...
Although filoviral infections are still occurring in different parts of the world, there are no effe...
Lloviu virus (LLOV), a novel filovirus detected in bats, is phylogenetically distinct from viruses i...
Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease charact...
Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable out...
Spatiotemporal aspects of filovirus entry and release are poorly understood. Lipid rafts act as func...
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The filoviruses Ebolavirus and Marburgviru...
The filoviruses Ebolavirus and Marburgvirus are among the deadliest viral pathogens known to infect ...
International audienceThere are no approved medications for the treatment of Marburg or Ebola virus ...
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Ear...
Since their discovery, the Ebola and Marburg virus cause regular outbreaks with lethality in humans ...
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in humans f...
International audienceFiloviruses are important pathogens that cause severe and often fatal hemorrha...
Filoviruses cause severe hemorrhagic fever in humans with high case-fatality rates. The cellular fac...
Lipid-enveloped viruses contain a lipid bilayer coat that protects their genome and helps to facilit...
Abstract: Ebola- and marburgviruses are highly pathogenic filoviruses and causative agents of viral ...
Although filoviral infections are still occurring in different parts of the world, there are no effe...
Lloviu virus (LLOV), a novel filovirus detected in bats, is phylogenetically distinct from viruses i...
Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease charact...
Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable out...