RESEARCH ARTICLE Acute oral toxicity and ant f J

Full list of author information is available at the end of the articlethe world´s population. The efficacy of medicinal plant in the management of diseases is indubitable. The World Health Organization estimated that 80 % of the population of developing countries, continues to use traditional medicine in primary medical problems. Several plants are typically and the population does not care, believing that if the mater-ial has being used so far, it should be devoid of toxicity [1]. Information on the toxicity of the plants is very important as baseline before further exploring its development as a new herbal medicine [2]. Standard experimental methods are useful for the vali-dation of ethnopharmacological knowledge regarding herbal medicine. Many studies are carried out to validate the use of medicinal plants in an effective and safe wa