Original Article Chronic kidney disease is prevalent in Chinese patients admitted with verified cerebrovascular lesions and predicts short-term prognosis

Objective. Recent studies have identified chronic kidney disease (CKD) as an important risk factor for vasculopa-thies. While the link between CKD and cardiovascular events is well established, the link with cerebrovascular lesions (CVL) has been less well described. Methods. We studied the prevalence and prognostic im-portance of CKD in 1014 incident Chinese patients admit-ted with verified computerized tomography (CT) or magnetic resonance imaging (MRI) CVL (within the last 7 days). Laboratory data included the urinary microalbu-min-to-creatinine ratio, routine urinalysis, fasting plasma glucose, serum creatinine, uric acid and other measures. Estimated glomerular filtration rate was calculated (using the modification of diet in renal disease formula) and CKD stages were classified according to kidney disease outcome quality initiative (K/DOQI) guidelines. Patients were fol-lowed for 30 days and any neurological sequelae were recorded. Results. A total of 1014 patients were enrolled (455 females, aged 68.56 612.17 years). Among these, 708 had ischemic stroke, 197 hemorrhagic stroke and 109 had transient cere-bral ischemic attack. Microalbuminuria was detected in 11.2 % of patients, while 24.8 % had proteinuria. Of all pa