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A 49-year-old right-handed woman without family his-tory of neurodegenerative conditions was evaluated for fluency and naming difficulties that developed over 10 years. Neurologic examination was normal except for nonfluent dysphasia. Brain MRI was normal without focal cortical atrophy. Brain metabolic PET scan dem-onstrated left temporal hypofunction (figure). Primary progressive aphasia (PPA) is a clinical syndrome that erodes speech and language. The case was diagnosed logopenic variant of PPA because of word-finding difficulties and decreased output. Alz-heimer disease and frontotemporal lobar degenera-tion are the most common etiologies.1 Functional imaging may reveal hypometabolism even if struc-tural imaging is normal. REFERENCE 1. Mesulam MM. Slowly progressive aphasia without gener-alized dementia. Ann Neurol 1982;11:592–598. Figure 18F-FDG PET scan exhibiting marked focal hypometabolism in the left superior temporal, inferior parietal, and lateral thalamic regions Address correspondence and reprint requests to Dr. Sulta