Transmission of human immunodeficiency virus infection presumed to have occurred via female homosexual contact. Clin Infect Dis 17

We describe a 24-year-old woman infected with the human immunodeficiency virus (HIV) whose sole risk behavior was prior sexual contact with an HIV-infected woman. Our patient's clinical course suggests that viral transmission occurred during the beginning of their sexual relationship. Our case, combined with those previously reported, provides evidence that female homosexual activity can be a risk behavior for acquisition of HIV infection. Seroprevalence studies, however, have not provided evidence for transmission of HIV by this behavior. These studies, combined with the sparse number of individual case reports, suggest that female homo-sexual activity is an inefficient mechanism of HIV transmission. Transmission of the human immunodeficiency virus (HIV) by female-to-female sexual activity appears to be inef-ficient. There are only four reported patients for whom HIV was presumed to have been acquired from female-to-female sexual activity [1-4]. In addition, studies of HIV seropreva-lence among donors of blood products [5] have not estab-lished a relationship between this type of sexual activity an