Influence of cholesterol status on blood lipid and lipoprotein enzyme responses to aerobic exercise

James Rohack. Influence of cholesterol status on blood lipid and lipoprotein enzyme responses to aerobic exercise. J Appl Physiol 89: 472–480, 2000.—To compare postexercise changes in plasma lipids and lipoprotein enzymes in 13 hypercholesterolemic (HC) and 12 normocholesterolemic men [total cholesterol (TC) 252 6 5 vs. 179 6 5 mg/dl], fasting blood samples were obtained 24 h before, immediately, 24, and 48 h after a single bout of treadmill walking (70 % peak O2 consumption, 500 kcal expenditure). Significant findings (P, 0.05 for all) for plasma volume-adjusted lipid and enzyme variables were that TC, low-density-lipoprotein cho-lesterol, and cholesterol ester transfer protein activity were higher in the HC group but did not influence the lipid re-sponses to exercise. Across groups, TC was transiently re-duced immediately after exercise but returned to baselin