Clinical trial...

Background: Clinical trials are a critical resource for the discovery of new prevention, diagnostic, and treatment methods for cancer. The most effective prevention and treatment modalities are based on previous clinical trial results. However, participation in clinical trials is underrepresented by racial/ethnic minority populations, AsianAmericans in particular. AsianAmericans are the least represented of any ethnic groups in clinical trials. The purpose of this study is to develop and evaluate a culturally and linguistically appropriate community-based educational intervention to increase knowledge of and intent to participate in cancer clinical trials among underrepresented Chinese Americans. Methods:Community-Based Participatory Research approachwas used to guide the development, cultural tailoring, implementation, and evaluation of clinical trial intervention. First, 22 Asian community representa-tives were recruited as community health educators (CHE) who received 12-hour training on clinical trial education. Second, 262memberswere recruited from11Chinese community organizations.Of those recruited, a total of 247 eligibleChinese enrolled andparticipated in the clinical trial educationdeliveredby trainedCHEs. Participants completed pretest before and posttest after the intervention. Results: Fifteen of 21 measures of clinical trial knowledge showed significant changes post the interventio