Abstract P and S body waves from microearthquakes in the New Madrid Seismic Zone (NMSZ) are investigated at selected sites in an effort to understand wave prop-agation from future large earthquakes. Earthquake body waveforms display distinc-tive features that constrain the nature of P- and S-wave local site responses and wave propagation within the unconsolidated Mississippi embayment sediments. Modeling of the waveforms demonstrates that a near-surface low-velocity zone is characteristic of structure within the upper 60 m of the sedimentary column and produces large P-and S-wave resonance effects that can be used to infer near-site conditions. Site resonance effects change because of velocity heterogeneity between individual re-ceivers but...