A Review of Inverted Papilloma at a Tertiary Centre: A Six-Year Experience

Copyright © 2013 Chiun Kian Chai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objectives: To evaluate the clinical presentation and treatment outcome of all patients treated for inverted papilloma at the University Malaya Medical Centre, Malaysia. Methods: A retrospective review of 22 patients with inverted papil-loma, treated at our centre, from 1st January 2005 to 31st August 2011. The demographic data, clinical features, radio-logical findings, surgical procedures, recurrent rate and malignant transformation were assessed. Result: The com-monest presentation was a unilateral nasal blockage, comprising 77.3 % cases. A total of 19 patients had undergone en-doscopic surgery while three patients had open surgery performed. The mean duration of the follow-up period was 30.5 months. Seven (31.7%) patients were detected of tumour recurrence during the entire course of follow-up. However, throughout the follow-up period, none had demonstrated malignant transformation. Conclusion: Endoscopic medial maxillectomy is a well-accepted approach in treating inverted papilloma. Nevertheless, open surgery still plays an im-portant role in extensive diseases and in cases of malignancy. Unilateral nasal obstruction is the most important symp-tom. Repeated pre-operative biopsy or perhaps frozen section of intraoperative biopsies is necessary to avoid misdiag-nosis. Krouse stage II disease showed the highest recurrent rate of 18.2%. Lifelong follow-up and emphasis on adher