SARCOIDOSIS WITH INVOLVEMENT OF THE PITUITARY GLAND*

SARCOIDOSIS is a fairly common disease. However, pituitary involvement by sarcoidosis is exceedingly rare. W e have observed a patient with proved sarcoidosis with probable involvement of the pituitary gland. CASE REPORT A 32 year old white male machinist was first admitted to this hospital in 1945 because of small lumps in the pretibial area which were diagnosed as erythema no-dosum. The x-ray of the chest showed a distinct hilar lymphadenopathy. No glands were palpable, and there was no testicular atrophy. Sputa were negative for fungi and tuberculosis. The patient's next admission was in 1951 because of fatigue and cough. The liver was 5 cm. below the costal margin, and the spleen was palpable. There was dryness of the skin, and the hair was thin. Palpable lymph nodes were present. X-ray of the chest showed linear infiltrations extending from the hili to both bases. X-rays of the hands were normal. Total protein was 6.3 gm.%; albumin, 3.4; globu-lin, 2.9; A /G ratio, 1.2; serum calcium, 10 mg./lOO c.c. Alkaline phosphatase wa