Renal Function after Partial Nephrectomy for Renal Cell Carcinoma in Solitary Kidney

Purpose: Renal cell carcinoma (RCC) in solitary kidney is an absolute indication for partial nephrectomy. We evaluated the renal function after partial nephrectomy for renal cell carcinoma in a solitary kidney. Materials and Methods: Partial nephrectomy was performed in 14 patients with localized sporadic RCCs that developed in a solitary kidney between January 1993 and December 2005. In 8 patients (57%), the contralateral kidney had been surgically removed. In the remaining 6 patients, 4 had a contralateral nonfunctioning kidney (29%) and 2 had nephrolithiasis (14%). Three patients were treated with enucleation, and partial nephrec-tomy was done in 11 patients. The recorded variables we studied were the preoperative and postoperative serum creatinine levels, whether renal ischemia and hypothermia was used, the duration of renal ischemia and the percent of renal parenchyma that was resected. Results: At mean follow-up of 55.6 months (range: 16.3-106.6), the mean serum creatinine had increased from 1.03mg/dl preoperatively to 1.2