RUDZINSKA et al. (1964) described several unidentified structures in the cytoplasm of Leishmania donovani which included a large ovoid structure which they suggested may represent a lysosome. Biochemical studies have shown that lysosomes of liver, kidney, and various other cells contain several hydrolytic enzymes, including acid phosphatase (DE DUW, 1959, 1963). The application of the lead-glycerophosphate technique for the histochemical demonstration f acid phosphatase activity (GOMORI, 1952) has been found to be a useful method to demonstrate lysosomes at an electron microscopical level (NovzKoFF, 1963; SCARP~LLI and KANCZAK, 1965). The present report describes the ultrastmcn~al localization of acid phosphatase activity in the leishmanial...
Bloodstream forms of African trypanosomes, which endocytose macromolecules exclusively through their...
A method for determining the distribution of lysozyme activity of animal tissues in situ has been de...
In this study we take advantage of recently developed methods using J774 macrophages to prepare enri...
Lysosomes, as demonstrated biochemically in the liver, are subcellular particles con-taining a group...
Acid phosphatase activity was detected in the Malpighian tubules of the bloodsucking hemipteran, Tri...
In a previous publication, we described the purification of a membrane-bound acid phosphatase of Lei...
This study represents the first example of immunological localization of lysosomal acid phosphatase....
Includes bibliographical references (pages 30-36)Electron microscope histochemical and biochemical p...
Fractionation techniques, based on zonal centrifugation in density gradients, were developed for exa...
Localization of acid phosphatase, $-glucuronidase and N-acetyl-fl-glucosamin idase has beets studied...
First electron micrograph of a lysosome-rich fraction from rat liver. From Novikoff et al., 1956. J....
Evidence is presented for the occurrence of glycosomes (organelles resembling peroxisomes) in four m...
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the ...
Electron microscope cytochemical and simple morphometric studies have permitted an estimate to be ma...
Four monoclonal antibodies (McAbs) were generated against the soluble extracellular acid phosphatase...
Bloodstream forms of African trypanosomes, which endocytose macromolecules exclusively through their...
A method for determining the distribution of lysozyme activity of animal tissues in situ has been de...
In this study we take advantage of recently developed methods using J774 macrophages to prepare enri...
Lysosomes, as demonstrated biochemically in the liver, are subcellular particles con-taining a group...
Acid phosphatase activity was detected in the Malpighian tubules of the bloodsucking hemipteran, Tri...
In a previous publication, we described the purification of a membrane-bound acid phosphatase of Lei...
This study represents the first example of immunological localization of lysosomal acid phosphatase....
Includes bibliographical references (pages 30-36)Electron microscope histochemical and biochemical p...
Fractionation techniques, based on zonal centrifugation in density gradients, were developed for exa...
Localization of acid phosphatase, $-glucuronidase and N-acetyl-fl-glucosamin idase has beets studied...
First electron micrograph of a lysosome-rich fraction from rat liver. From Novikoff et al., 1956. J....
Evidence is presented for the occurrence of glycosomes (organelles resembling peroxisomes) in four m...
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the ...
Electron microscope cytochemical and simple morphometric studies have permitted an estimate to be ma...
Four monoclonal antibodies (McAbs) were generated against the soluble extracellular acid phosphatase...
Bloodstream forms of African trypanosomes, which endocytose macromolecules exclusively through their...
A method for determining the distribution of lysozyme activity of animal tissues in situ has been de...
In this study we take advantage of recently developed methods using J774 macrophages to prepare enri...