HMMER web server: interactive sequence similarity searching. Nucleic Acids Res 39:W29–W37. http:// dx.doi.org/10.1093/nar/gkr367

HMMER is a software suite for protein sequence similarity searches using probabilistic methods. Previously, HMMER has mainly been available only as a computationally intensive UNIX command-line tool, restricting its use. Recent advances in the soft-ware, HMMER3, have resulted in a 100-fold speed gain relative to previous versions. It is now feasible to make efficient profile hidden Markov model (pro-file HMM) searches via the web. A HMMER web serve