The Molecular Weight Distribution of the Chondroitin Sulfates of Bovine and Whale Nasal Septum

Chondroitin sulfates were quantitatively extracted from bovine and whale nasal septum without indiscriminate depolymerization by treatment with 0.5 M sodium hydroxide contain-ing 0.26 M sodium borohydride at 3-5°C for 10 days. The reducing-end xylitol of the glyco-saminoglycans was accurately determined by a microchemical method which had been developed for the separation and determination of the reducing-end alditols of reduced polysaccharides with high molecular weight (Yamaguchi, H., Inamura, S., & Makino, K. (1976) /. Biochem