Azoospermia in vitro fertilization. Summary

response to this problem in the last years there has been an intense development in diagnostic and therapeutic methods defined as Assisted Reproductive Technologies (ART) connected with an increased risk of iatrogenic disorders in mother and child. The objective of this study was to assess the outcome of Natural Procreative Technology (NPT) treatment in couples diagnosed with infertility. Material and Methods. A total of 412 infertile couples, diagnosed and treated from January 2009 to November 2010 in the NAPROMEDICA center of infertility treatment in Bialystok, were included. NPT, a standardized investigation met-hod for diagnosis, and treatment of reproductive function disorders associated with infertility were implemented. The Creighton Model FertilityCare System (CrMS), a standardized method of mens-trual cycle monitoring (bleeding and cervical fluid score) was applied. Azoospermia in men and insufficient cooperation in NPT procedures were criteria of exclusion. Results. The average female age was 33.7 years, the mean duration of attempting to conceive was 4.9 years, and 29.4 % of couples had previously attempted treatment with assisted reproductive technology (ART). Positive results of pregnancy tests were obtained in 70/412 couples (17.0%); 23.88 % in the youngest women subgroup (25 – 29 years) and 6.52 % in the oldest women subgroup (40 – 47 years). One twin pregnancy was observed in a group of 70 couples (1.43%) treated with NPT. In the subgroup of couples with conception the mean time from the beginning of NPT treatment to positive pregnancy tests was 6.6 ± 5.3 months (95 % CI 5.4 – 7.9 months) including a 3 month diagnostic stage (CrMS). Conclusions. NPT treatment, assessed in a short period of time, may be efficient in achieving a conception in certain couples including those af-ter unsuccessful ART. NPT treatment is associated with rare multiple pregnancies