Genotypes on Growth Traits in F2 Population Between Landrace and Jeju Native Black Pig

Genetic polymorphisms was investigated at five single nucleotide polymorphisms (SNP) sites in four porcine genes (ADCYAP1R1, FABP3, MC4R, and MYL2) and analyzed their statistical association with growth traits in F2 reciprocal-crossbred population between Landrace and Jeju native black pig (JNP). All populations, JNP, Landrace and their F2 were polymorphic for all five SNP loci tested, however, the homozygote T/T of FABP3 g.-158T>C and the homozygote G/G of ADCYAP1R1 intron 2 337A>G were not found in JNP and Landrace, respectively. The genotypes of ADCYAP1R1 were significantly associated with body weights (BW) at 3 weeks and at 20 weeks (P<0.05), respectivley, those of FABP3 g.-135delT were associated with late average daily gain (LADG) (P<0.01), and those of FABP3 g.-158T>G were associated with body weights during late growth period such as, BW20 and LADG (P<0.01). Those of MC4R were also significantly associated with BW10 suggesting by the difference of early average daily gain (EADG) (P<0.05), and with LADG (P<0.01). The body length of F2 animals was affected by the genotypes of ADCYAP1R1, MC4R, and MYL2 (P<0.05), respectively. Among these, MC4R A/A homozygotes showed over 3 cm longer in body length than those of other genotypes. As the useful basic information