human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med 2010; 2: 52ra72. 3 Holz O, Tal-Singer R, Kanniess F, et al. Validation of the human ozone challenge model as a tool for assessing anti-inflammatory drugs in early development. J Clin Pharmacol 2005; 45: 498–503. 4 Holz O, Khalilieh S, Ludwig-Sengpiel A, et al. SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects. Eur Respir J 2010; 35: 564–570. 5 Kirsten A, Watz H, Kretschmar G, et al. Efficacy of the pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects – a double blind, randomized, placebo-controlled, cross-over clinical trial. Pulm Pharmacol Ther 2011; 24: 555–55...
Introduction: Ground level ozone is a respiratory irritant component of air pollution. Exercise is a...
Ozone therapy is an effective medical treatment for different diseases like mucositis, psoriasis, ac...
BackgroundExposure to ozone (O3) is associated with increased risk of exacerbations of asthma, but t...
This study aimed to test the utility of the ozone challenge model for profiling novel compounds desi...
INTRODUCTION: The ozone challenge model can be used to assess the efficacy of novel anti-inflammator...
Full list of author information is available at the end of the articleBackground Ozone (O3) is an im...
To determine the safety and tolerability of a novel selective CXCR2 antagonist and assess its pharma...
Ozone and lipopolysaccharide (LPS) are environmental pollutants with adverse health effects noted in...
Background: The ozone challenge model can be used to assess the efficacy of anti-inflammatory compou...
Airway hyperresponsiveness (AHR) and airway inflammation are key pathophysiological features of many...
Epidemiological and challenge studies in healthy subjects and in individuals with asthma highlight t...
Rationale: Exposure to ozone causes a decrease in spirometric lung function and an increase in airwa...
BAL neutrophil counts at 48 h post-O3exposure in WT and TLR4−/− mice. WT and TLR4−/− mice were expos...
Figure S1. Human iPSC-MSCs showed no effects on murine steroid-resistant airway inflammation at 4 h ...
Asthma is a known risk factor for acute ozone-associated respiratory disease. Ozone (O3) causes an i...
Introduction: Ground level ozone is a respiratory irritant component of air pollution. Exercise is a...
Ozone therapy is an effective medical treatment for different diseases like mucositis, psoriasis, ac...
BackgroundExposure to ozone (O3) is associated with increased risk of exacerbations of asthma, but t...
This study aimed to test the utility of the ozone challenge model for profiling novel compounds desi...
INTRODUCTION: The ozone challenge model can be used to assess the efficacy of novel anti-inflammator...
Full list of author information is available at the end of the articleBackground Ozone (O3) is an im...
To determine the safety and tolerability of a novel selective CXCR2 antagonist and assess its pharma...
Ozone and lipopolysaccharide (LPS) are environmental pollutants with adverse health effects noted in...
Background: The ozone challenge model can be used to assess the efficacy of anti-inflammatory compou...
Airway hyperresponsiveness (AHR) and airway inflammation are key pathophysiological features of many...
Epidemiological and challenge studies in healthy subjects and in individuals with asthma highlight t...
Rationale: Exposure to ozone causes a decrease in spirometric lung function and an increase in airwa...
BAL neutrophil counts at 48 h post-O3exposure in WT and TLR4−/− mice. WT and TLR4−/− mice were expos...
Figure S1. Human iPSC-MSCs showed no effects on murine steroid-resistant airway inflammation at 4 h ...
Asthma is a known risk factor for acute ozone-associated respiratory disease. Ozone (O3) causes an i...
Introduction: Ground level ozone is a respiratory irritant component of air pollution. Exercise is a...
Ozone therapy is an effective medical treatment for different diseases like mucositis, psoriasis, ac...
BackgroundExposure to ozone (O3) is associated with increased risk of exacerbations of asthma, but t...