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days, beginning in the pelvic limbs and progress-ing to involve all limbs and rendering the cat function improved significantly over 2e3 weeks ised muscle atrophy (paraspinal and appendicu-and skin sensation were well preserved. Cranial nerve reflexes were normal and no change in motor neuropathy. A cause could not be identi-and IgM levels, on two consecutive blood sam-ples taken 3 weeks apart. Journal of Feline Medicine and Surgery (2008) 10, 603e607 doi:10.1016/j.jfms.2008.03.008lar muscles) with sparing of the cranialand took 3 months to return to normality. The cat was vaccinated as a kitten, but not since, and lived exclusively indoors. No abnormalities were detected during general physical examination, except marked, general-fied through examination of serum biochemistry and complete blood cell count. Serology for evidence of exposure to feline coronavirus was negative. Exposure to toxoplasmosis was also negative as evidenced by normal serum IgGnon-ambulatory, before stabilising the following week. The cat was examined 8 days after becom-ing unable to walk. The cat had had a similar episode at 6 months of age; at that time, motor vocalisation was reported. The clinical findings were consistent with a generalised neuromuscular disorder, for exam-ple, a myopathy, junctionopathy or a primarilyAwas presented to theinary School Hospita gressive loss of motor functio Clinical signs appeared insmusculature. The neurolog revealed flaccid tetraparesis b