CLINICAL TRIALS AND OBSERVATIONS

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era.

Santiago Montes-Moreno
Mark J Routbort
Elijah J Lohman
Bedia A Barkoh
Rashmi Kanagal-Shamanna
Carlos E Bueso-Ramos
Rajesh R Singh
L Jeffrey Medeiros
Raja Luthra
Keyur P Patel

January 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era

Santiago Montes-Moreno (135753)
Mark J. Routbort (3818305)
Elijah J. Lohman (5754179)
Bedia A. Barkoh (4326214)
Rashmi Kanagal-Shamanna (5754182)
Carlos E. Bueso-Ramos (258439)
Rajesh R. Singh (4326217)
L. Jeffrey Medeiros (194621)
Raja Luthra (774811)
Keyur P. Patel (3818284)

September 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia

Gelsi-Boyer, Véronique
Trouplin, Virginie
Adélaïde, José
Bonansea, Julien
Cervera, Nathalie
Carbuccia, Nadine
Lagarde, Arnaud
Prebet, Thomas
Nezri, Meyer
Sainty, Danielle
Olschwang, Sylviane
Xerri, Luc
Chaffanet, Max
Mozziconacci, Marie-Joëlle
Vey, Norbert
Birnbaum, Daniel

June 2009

International audienceThe myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haema...

Distinct Clinical and Biological Features of De Novo Acute Myeloid Leukemia with Additional Sex Comb-Like 1 (Asxl1) Mutations

周文堅
CHOU, WEN-CHIEN

June 2011

Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid mali...

ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype.

Prats-Martín, Concepción
Burillo-Sanz, Sergio
Morales-Camacho, Rosario M
Pérez-López, Olga
Suito, Milagros
Vargas, Maria T
Caballero-Velázquez, Teresa
Carrillo-Cruz, Estrella
González, José
Bernal, Ricardo
Pérez-Simón, José A

March 2020

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its...

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Boultwood J
Perry J
Pellagatti A
Fernandez Mercado M
Fernandez Santamaria C
Calasanz MJ
Larrayoz MJ
Garcia Delgado M
Giagounidis A
Jädersten M
Killick S
Hellström Lindberg E
Wainscoat J.S.
MALCOVATI, LUCA
DELLA PORTA, MATTEO GIOVANNI
CAZZOLA, MARIO

January 2010

The identification of those genes that are frequently mutated in malignancies is essential for a ful...

Acquired mutations in ASXL1 in acute myeloid leukemia: Prevalence and prognostic value

Pratcorona, M. (Marta)
Abbas, S. (Saman)
Sanders, M.A. (Mathijs)
Koenders, J.E. (Jasper)
Kavelaars, F.G. (François)
Erpelinck, C.A.J. (Claudia)
Zeilemakers, A. (Annelieke)
Löwenberg, B. (Bob)
Valk, P.J.M. (Peter)

March 2012

Somatic mutations in the additional sex comb-like 1 (ASXL1) gene have been described in various type...

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Boultwood J
Perry J
Pellagatti A
Fernandez Mercado M
Fernandez Santamaria C
Calasanz MJ
Larrayoz MJ
Garcia Delgado M
Giagounidis A
Jädersten M
Killick S
Hellström Lindberg E
Wainscoat J.S.
MALCOVATI, LUCA
DELLA PORTA, MATTEO GIOVANNI
CAZZOLA, MARIO

January 2010

The identification of those genes that are frequently mutated in malignancies is essential for a ful...

Risk factors affect accurate prognosis in ASXL1-mutated acute myeloid leukemia

Yi Fan
Linxiao Liao
Yajun Liu
Zhenzhen Wu
Chong Wang
Zhongxing Jiang
Shujuan Wang
Yanfang Liu

October 2021

Abstract Background The epigenetic regulator additional sex combs-like 1 (ASXL1) is an adverse progn...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome

Chen, T-C
蔡偉

April 2017

Recently, mutations of the additional sex comb-like 1 (ASXL1) gene were identified in patients with ...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Genomics of acute myeloid leukemia diagnosis and pathways

Bullinger, L.
Döhner, K.
Döhner, H.

March 2017

In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms, including acu...

Acute myeloid leukaemia genomics

Medinger, Michael
Passweg, Jakob R.

January 2017

Acute myeloid leukaemia (AML) is a biologically complex, molecularly and clinically heterogeneous di...

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era.

Santiago Montes-Moreno
Mark J Routbort
Elijah J Lohman
Bedia A Barkoh
Rashmi Kanagal-Shamanna
Carlos E Bueso-Ramos
Rajesh R Singh
L Jeffrey Medeiros
Raja Luthra
Keyur P Patel

January 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era

Santiago Montes-Moreno (135753)
Mark J. Routbort (3818305)
Elijah J. Lohman (5754179)
Bedia A. Barkoh (4326214)
Rashmi Kanagal-Shamanna (5754182)
Carlos E. Bueso-Ramos (258439)
Rajesh R. Singh (4326217)
L. Jeffrey Medeiros (194621)
Raja Luthra (774811)
Keyur P. Patel (3818284)

September 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia

Gelsi-Boyer, Véronique
Trouplin, Virginie
Adélaïde, José
Bonansea, Julien
Cervera, Nathalie
Carbuccia, Nadine
Lagarde, Arnaud
Prebet, Thomas
Nezri, Meyer
Sainty, Danielle
Olschwang, Sylviane
Xerri, Luc
Chaffanet, Max
Mozziconacci, Marie-Joëlle
Vey, Norbert
Birnbaum, Daniel

June 2009

International audienceThe myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haema...

Distinct Clinical and Biological Features of De Novo Acute Myeloid Leukemia with Additional Sex Comb-Like 1 (Asxl1) Mutations

周文堅
CHOU, WEN-CHIEN

June 2011

Mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid mali...

ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype.

Prats-Martín, Concepción
Burillo-Sanz, Sergio
Morales-Camacho, Rosario M
Pérez-López, Olga
Suito, Milagros
Vargas, Maria T
Caballero-Velázquez, Teresa
Carrillo-Cruz, Estrella
González, José
Bernal, Ricardo
Pérez-Simón, José A

March 2020

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its...

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Boultwood J
Perry J
Pellagatti A
Fernandez Mercado M
Fernandez Santamaria C
Calasanz MJ
Larrayoz MJ
Garcia Delgado M
Giagounidis A
Jädersten M
Killick S
Hellström Lindberg E
Wainscoat J.S.
MALCOVATI, LUCA
DELLA PORTA, MATTEO GIOVANNI
CAZZOLA, MARIO

January 2010

The identification of those genes that are frequently mutated in malignancies is essential for a ful...

Acquired mutations in ASXL1 in acute myeloid leukemia: Prevalence and prognostic value

Pratcorona, M. (Marta)
Abbas, S. (Saman)
Sanders, M.A. (Mathijs)
Koenders, J.E. (Jasper)
Kavelaars, F.G. (François)
Erpelinck, C.A.J. (Claudia)
Zeilemakers, A. (Annelieke)
Löwenberg, B. (Bob)
Valk, P.J.M. (Peter)

March 2012

Somatic mutations in the additional sex comb-like 1 (ASXL1) gene have been described in various type...

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

Boultwood J
Perry J
Pellagatti A
Fernandez Mercado M
Fernandez Santamaria C
Calasanz MJ
Larrayoz MJ
Garcia Delgado M
Giagounidis A
Jädersten M
Killick S
Hellström Lindberg E
Wainscoat J.S.
MALCOVATI, LUCA
DELLA PORTA, MATTEO GIOVANNI
CAZZOLA, MARIO

January 2010

The identification of those genes that are frequently mutated in malignancies is essential for a ful...

Risk factors affect accurate prognosis in ASXL1-mutated acute myeloid leukemia

Yi Fan
Linxiao Liao
Yajun Liu
Zhenzhen Wu
Chong Wang
Zhongxing Jiang
Shujuan Wang
Yanfang Liu

October 2021

Abstract Background The epigenetic regulator additional sex combs-like 1 (ASXL1) is an adverse progn...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome

Chen, T-C
蔡偉

April 2017

Recently, mutations of the additional sex comb-like 1 (ASXL1) gene were identified in patients with ...

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Gelsi-Boyer, Véronique
Brecqueville, Mandy
Devillier, Raynier
Murati, Anne
Mozziconacci, Marie-Joelle
Birnbaum, Daniel

January 2012

International audienceABSTRACT: The ASXL1 gene is one of the most frequently mutated genes in malign...

Genomics of acute myeloid leukemia diagnosis and pathways

Bullinger, L.
Döhner, K.
Döhner, H.

March 2017

In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms, including acu...

Acute myeloid leukaemia genomics

Medinger, Michael
Passweg, Jakob R.

January 2017

Acute myeloid leukaemia (AML) is a biologically complex, molecularly and clinically heterogeneous di...

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era.

Santiago Montes-Moreno
Mark J Routbort
Elijah J Lohman
Bedia A Barkoh
Rashmi Kanagal-Shamanna
Carlos E Bueso-Ramos
Rajesh R Singh
L Jeffrey Medeiros
Raja Luthra
Keyur P Patel

January 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era

Santiago Montes-Moreno (135753)
Mark J. Routbort (3818305)
Elijah J. Lohman (5754179)
Bedia A. Barkoh (4326214)
Rashmi Kanagal-Shamanna (5754182)
Carlos E. Bueso-Ramos (258439)
Rajesh R. Singh (4326217)
L. Jeffrey Medeiros (194621)
Raja Luthra (774811)
Keyur P. Patel (3818284)

September 2018

ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms...

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia

Gelsi-Boyer, Véronique
Trouplin, Virginie
Adélaïde, José
Bonansea, Julien
Cervera, Nathalie
Carbuccia, Nadine
Lagarde, Arnaud
Prebet, Thomas
Nezri, Meyer
Sainty, Danielle
Olschwang, Sylviane
Xerri, Luc
Chaffanet, Max
Mozziconacci, Marie-Joëlle
Vey, Norbert
Birnbaum, Daniel

June 2009

International audienceThe myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haema...

CLINICAL TRIALS AND OBSERVATIONS

Abstract

Extracted data

CLINICAL TRIALS AND OBSERVATIONS

Abstract

Extracted data

Related items

Related items