Assessment of a right-ventricular infundibulum-sparing approach in transatrial–transpulmonary repair of tetralogy of Fallot

OBJECTIVE: The study aimed to evaluate the outcome of transatrial–transpulmonary repair of tetralogy of Fallot in relation to a right-ventricular outflow tract (RVOT)-sparing surgery. METHODS: Based on the surgical management of right-ventricular outflow tract obstruction (RVOTO) at repair of tetralogy of Fallot, 140 children were retrospectively divided into three groups: (1) pulmonary valve (PV)-sparing, (2) infundibulum-sparing and (3) extended trans-annular patch (TAP). Clinical and echocardiographic outcome was assessed with regards to three equally divided study time eras between January 1994 and June 2010. RESULTS: Over a 15-year study period, median age decreased from 11 (2–101) to 5 (1–11) months (p < 0.001), whereas type of RVOT repair changed significantly between the first and the last era (group 1: 18–40%, group 2: 25–40 % vs group 3: 57–20 % (p = 0.002)). Mortality was 0%. Complications were mainly related to clinical restrictive RV physiology (27%) and arrhythmia (10%). This cardiac mor-bidity remained constant over the eras and was associated with younger age (p = 0.04), increased postoperative right ventricle/left ven-tricle (RV/LV) pressure ratio (p = 0.01) and type of RVOT repair at the cost of TAP (p = 0.03). Median follow-up of 8 years (1–16 years) showed an overall freedom from RVOT re-operation of 84 % and 73%, respectively at 5 and 10 years. Most re-operations were for re-sidual/recurrent RVOTO (12%) occurring more frequently in the latter era: 16 % versus 7 % in era 1 (p = 0.08). Late echocardiographic evaluation revealed a strong correlation between severity of pulmonary regurgitation and increased RV/LV size ratio, which was mainl