Draft genome sequence of an Aeromonas sp. Strain 159 clinical isolate that shows quorum-sensing activity

Aeromonas is a pathogenic organism that is often found to infect humans. Here we report the draft genome of a clinical isolate in Malaysia, Aeromonas sp. strain 159, which showsN-acylhomoserine lactone production. In the draft genome of strain 159, luxI and luxR homologue genes were found to be located at contig 47, and these genes are believed to be important for the quorum-sensing system present in this pathogen. Aeromonas has long been known to be associated with humandisease, especially diarrhea (1, 6). Strains of Aeromonas spp. can be isolated from various specimens from a patient’s body, including blood, pus, and peritoneal fluid (2). It has been reported previously that Aeromonas spp. rely on quorum sensing to regu-late the expression of virulence factors (9). Aeromonas spp. pose a threat to public health due to the emergence of antibiotic-resistant strains (4). In this study, the clinical Aeromonas sp. strain 159 was isolated from the stool sample of a patient admitted to the Uni-versity of Malaya Medical Center, Kuala Lumpur. We had re-ported earlier that this strain producedN-acylhomoserine lactone (AHL) molecules (2). Therefore, in order to further understan