Add to ORKGThe increasing prevalence of obesity in urban Indian children is indicative of an impending crisis of metabolic disorders. Although perturbations in the secretion of adipokines and inflammatory molecules in childhood obesity are well documented, the contri-bution of common variants of genes encoding them is not well investigated. We assessed the association of 125 common variants from 21 genes, encoding adipocytokines and inflammatory markers in 1,325 urban Indian children (862 normal weight [NW group] and 463 overweight/obese [OW/OB group]) and replicated top loci in 1,843 Indian children (1,399 NW children and 444 OW/OB children). Variants of four genes (PBEF1 [rs3801266] [P = 4.5 3 1024], IL6 [rs2069845] [P = 8.7 3 1024], LEPR [rs1137100...
BACKGROUND: Obesity is a multi-factorial chronic disorder. A considerable number of studies have bee...
BACKGROUND: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...
Background: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...
The increasing prevalence of obesity in urban Indian children is indicative of an impending crisis o...
The increasing prevalence of obesity in urban Indian children is indicative of an impending crisis o...
Context: Common intronic variants of the fat mass and obesity-associated (FTO) gene have been associ...
The aim: to study the contribution of single-nucleotide polymorphisms (SNP) of the leptin receptor (...
Hyperhomocysteinemia is regarded as a risk factor for cardiovascular diseases, diabetes and obesity....
variants with adiposity in adult Indian, its association in Indian children is yet to be confirmed....
Background: FTO variants are robustly associated with obesity and related traits in many population ...
Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in...
variants cause obesity analogous to rare mutations in the leptin, leptin receptor and MC4R genes. i...
Introduction. Increase in body weight is a gradual process that usually begins in childhood and in a...
Introduction. Increase in body weight is a gradual process that usually begins in childhood and in a...
FTO variants are robustly associated with obesity and related traits in many population and shown to...
BACKGROUND: Obesity is a multi-factorial chronic disorder. A considerable number of studies have bee...
BACKGROUND: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...
Background: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...
The increasing prevalence of obesity in urban Indian children is indicative of an impending crisis o...
The increasing prevalence of obesity in urban Indian children is indicative of an impending crisis o...
Context: Common intronic variants of the fat mass and obesity-associated (FTO) gene have been associ...
The aim: to study the contribution of single-nucleotide polymorphisms (SNP) of the leptin receptor (...
Hyperhomocysteinemia is regarded as a risk factor for cardiovascular diseases, diabetes and obesity....
variants with adiposity in adult Indian, its association in Indian children is yet to be confirmed....
Background: FTO variants are robustly associated with obesity and related traits in many population ...
Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in...
variants cause obesity analogous to rare mutations in the leptin, leptin receptor and MC4R genes. i...
Introduction. Increase in body weight is a gradual process that usually begins in childhood and in a...
Introduction. Increase in body weight is a gradual process that usually begins in childhood and in a...
FTO variants are robustly associated with obesity and related traits in many population and shown to...
BACKGROUND: Obesity is a multi-factorial chronic disorder. A considerable number of studies have bee...
BACKGROUND: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...
Background: Common variants in the FTO locus, and near MC4R locus, have been shown to have a robust ...