Add to ORKGDistinct classes of c-Kit–activating mutations differ in their ability to promote RUNX1-ETO–associated acute myeloid leukemi
The Kasumi-1 cell line is an intensively investigated model system of Acute Myeloid Leukemia with t(...
Several different mutations collaborate with the fusion proteins in core-binding factor acute myeloi...
SummaryWe here use knockin mutagenesis in the mouse to model the spectrum of acquired CEBPA mutation...
1 Distinct classes of c-Kit activating mutations differ in their ability to promote RUNX1-ETO-associ...
t (8;21)(q22;q22) is the most frequently detected cytogenetic abnormality in patients with acute mye...
AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasm
A subset of AML-M2/M4Eo patients has been shown to carry c-kit mutations suggesting that myelomonobl...
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome with a 20% risk of...
SL3-3 murine leukemia virus is a potent inducer of T-lymphomas in mice. Using inbred NMRI mice, it w...
BackgroundMinimally differentiated acute myeloid leukemia is heterogeneous in karyotype and is defin...
Somatic RUNX1 mutations are found in approximately 10% of patients with de novo acute myeloid leukem...
Background. The RUNX1 (AML1) gene is a frequent mutational target in myelodysplastic syndromes and a...
AML1/RUNX1 is implicated in leukemo-genesis on the basis of the AML1-ETO fusion transcript as well a...
SummaryThe t(8;21) and inv(16) chromosomal aberrations generate the oncoproteins AML1-ETO (A-E) and ...
myelodysplastic syndromes (MDS) and myeloproliferative neoplasm (MPN). The latter two diseases have ...
The Kasumi-1 cell line is an intensively investigated model system of Acute Myeloid Leukemia with t(...
Several different mutations collaborate with the fusion proteins in core-binding factor acute myeloi...
SummaryWe here use knockin mutagenesis in the mouse to model the spectrum of acquired CEBPA mutation...
1 Distinct classes of c-Kit activating mutations differ in their ability to promote RUNX1-ETO-associ...
t (8;21)(q22;q22) is the most frequently detected cytogenetic abnormality in patients with acute mye...
AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasm
A subset of AML-M2/M4Eo patients has been shown to carry c-kit mutations suggesting that myelomonobl...
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome with a 20% risk of...
SL3-3 murine leukemia virus is a potent inducer of T-lymphomas in mice. Using inbred NMRI mice, it w...
BackgroundMinimally differentiated acute myeloid leukemia is heterogeneous in karyotype and is defin...
Somatic RUNX1 mutations are found in approximately 10% of patients with de novo acute myeloid leukem...
Background. The RUNX1 (AML1) gene is a frequent mutational target in myelodysplastic syndromes and a...
AML1/RUNX1 is implicated in leukemo-genesis on the basis of the AML1-ETO fusion transcript as well a...
SummaryThe t(8;21) and inv(16) chromosomal aberrations generate the oncoproteins AML1-ETO (A-E) and ...
myelodysplastic syndromes (MDS) and myeloproliferative neoplasm (MPN). The latter two diseases have ...
The Kasumi-1 cell line is an intensively investigated model system of Acute Myeloid Leukemia with t(...
Several different mutations collaborate with the fusion proteins in core-binding factor acute myeloi...
SummaryWe here use knockin mutagenesis in the mouse to model the spectrum of acquired CEBPA mutation...