Ebenhoh O. Systems approaches to modelling pathways and networks. Brief Funct Genomics

It has become commonly accepted that systems approaches to biology are of outstanding impor-tance to gain understanding from the vast amount of data which is presently being generated by advancing high-throughput technologies. The diversity of methods to model pathways and networks has significantly expanded over the past two decades. Modern and traditional approaches are equally important and recent activities aim at integrating the advantages of both. This integration is of partic-ular importance since most available methods are specialised to particular systems or problems. The rapid progress of the field of theoretical systems biology, however, demonstrates how our fundamental theoretical understanding of biology is gaining momentum. The scientific community has apparently accepted the challenge to truly understand the principles of life