The androgen receptor (AR) is a critical effector of prostate cancer development and progression. Androgen-dependent prostate cancer is reliant on the function of AR for growth and progression. Most castration-resistant prostate cancer (CRPC) remains dependent on AR signaling for survival and growth. Ribosomal RNA (rRNA) is essential for both androgen-dependent and castration-resistant growth of prostate cancer cells. During androgen-dependent growth of prostate cells, androgen-AR signaling leads to the accumulation of rRNA. However, the mechanism by which AR regulates rRNA transcription is unknown. Here, investigation revealed that angiogenin (ANG), a member of the secreted ribonuclease superfamily, is upregulated in prostate cancer and me...
In the majority of castration-resistant prostate cancer (CRPC), prostate-specific antigen (PSA), pro...
Prostate cancer is the most commonly diagnosed cancer in men all over the world. Localized cancers i...
As prostate cancer progresses to castration-resistant disease, there is an increase in signal transd...
Angiogenin (ANG), originally identified as an angiogenic ribonuclease, has recently been shown to pl...
ABSTRACT We demonstrate that the androgen receptor (AR) regulates a transcriptional pro-gram of DNA ...
SummaryThe evolution of prostate cancer from an androgen-dependent state to one that is androgen-ind...
INSTRUCTIONS: Please enter one of the following Topic Classifications in the section below: Bioinfo...
Prostate cancer is one of the most common cancers diagnosed and the second leading cause of cancer r...
SummaryThe androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the ...
Since the growth of prostate cancer is androgen-sensitive, metastatic disease has been treated by ho...
Prostate cancer is a leading cause of cancer death in Canadian men. Prostate tumors initially depen...
Purpose: Progression to the castration-resistant state is the incurable and lethal end stage of pros...
Appraising the crucial role of androgen receptor (AR) in prostate cancer (PCa) initiation and progre...
Prostate cancer is a common and deadly disease for aging men in the United States. Normal prostate g...
The androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the commone...
In the majority of castration-resistant prostate cancer (CRPC), prostate-specific antigen (PSA), pro...
Prostate cancer is the most commonly diagnosed cancer in men all over the world. Localized cancers i...
As prostate cancer progresses to castration-resistant disease, there is an increase in signal transd...
Angiogenin (ANG), originally identified as an angiogenic ribonuclease, has recently been shown to pl...
ABSTRACT We demonstrate that the androgen receptor (AR) regulates a transcriptional pro-gram of DNA ...
SummaryThe evolution of prostate cancer from an androgen-dependent state to one that is androgen-ind...
INSTRUCTIONS: Please enter one of the following Topic Classifications in the section below: Bioinfo...
Prostate cancer is one of the most common cancers diagnosed and the second leading cause of cancer r...
SummaryThe androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the ...
Since the growth of prostate cancer is androgen-sensitive, metastatic disease has been treated by ho...
Prostate cancer is a leading cause of cancer death in Canadian men. Prostate tumors initially depen...
Purpose: Progression to the castration-resistant state is the incurable and lethal end stage of pros...
Appraising the crucial role of androgen receptor (AR) in prostate cancer (PCa) initiation and progre...
Prostate cancer is a common and deadly disease for aging men in the United States. Normal prostate g...
The androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the commone...
In the majority of castration-resistant prostate cancer (CRPC), prostate-specific antigen (PSA), pro...
Prostate cancer is the most commonly diagnosed cancer in men all over the world. Localized cancers i...
As prostate cancer progresses to castration-resistant disease, there is an increase in signal transd...