whether duplication of the c-fes gene occurs in the M3 subtypes exhibiting translocation t(15; 17) or other trans-locations and to assess the effect of such an event on c-fes expression. In summary, elevated expression of the c-fes gene is a fairly common finding in adult myeloid leukemia cells and can occur without detectable amplification of the c-fes gene. The potential contribu-tion of the c-fes proto-oncogene to the pathogenesis of myeloid leukemia re-mains to be established
Cellular oncogenes have been localized at the breakpoints of characteristic chromosomal rearrangemen...
Chromosomal translocations involving the Mixed-Lineage Leukaemia (MLL) gene underlie many human leuk...
Human probes identifying the cellular homologs of the v-ets gene, Hu-ets-1 and Hu-ets-2, and two pan...
The main purpose of this report is to provide a review of the present knowledge on the structure, fu...
The c-fes and c-fps genes are, respectively, the mammalian and avian proto-oncogenes which were ance...
AbstractA characteristic DNA rearrangement, the loss of an EcoRI cleavage site next to the 3́...
textabstractIn the process of hematopoietic development errors may occur, resulting in the aber¬rant...
AbstractThe c-fes protooncogene encodes a nonreceptor tyrosine kinase (Fes) implicated in cytokine r...
The c-fms proto-oncogene was shown to be expressed in human bone marrow and in differentiated blood ...
Total cellular RNA from a series of leukemic cell populations, both myeloid and lymphoid, as well as...
Amplification is one of the mechanisms by which cellular oncogenes may be altered in their function,...
The McDonough strain of the feline sarcoma virus contains a transforming gene (v-fms) which contains...
The chromosomal localization of c-myc sequences was determined by in situ hybridization in HL-60 cel...
Aim To assess the expression level of fms-like tyrosine kinase 3 (FLT3), the incidence of FLT3/inter...
Hemopoietic growth factors have been implicated in the pathogenesis of some myeloid leukemias when t...
Cellular oncogenes have been localized at the breakpoints of characteristic chromosomal rearrangemen...
Chromosomal translocations involving the Mixed-Lineage Leukaemia (MLL) gene underlie many human leuk...
Human probes identifying the cellular homologs of the v-ets gene, Hu-ets-1 and Hu-ets-2, and two pan...
The main purpose of this report is to provide a review of the present knowledge on the structure, fu...
The c-fes and c-fps genes are, respectively, the mammalian and avian proto-oncogenes which were ance...
AbstractA characteristic DNA rearrangement, the loss of an EcoRI cleavage site next to the 3́...
textabstractIn the process of hematopoietic development errors may occur, resulting in the aber¬rant...
AbstractThe c-fes protooncogene encodes a nonreceptor tyrosine kinase (Fes) implicated in cytokine r...
The c-fms proto-oncogene was shown to be expressed in human bone marrow and in differentiated blood ...
Total cellular RNA from a series of leukemic cell populations, both myeloid and lymphoid, as well as...
Amplification is one of the mechanisms by which cellular oncogenes may be altered in their function,...
The McDonough strain of the feline sarcoma virus contains a transforming gene (v-fms) which contains...
The chromosomal localization of c-myc sequences was determined by in situ hybridization in HL-60 cel...
Aim To assess the expression level of fms-like tyrosine kinase 3 (FLT3), the incidence of FLT3/inter...
Hemopoietic growth factors have been implicated in the pathogenesis of some myeloid leukemias when t...
Cellular oncogenes have been localized at the breakpoints of characteristic chromosomal rearrangemen...
Chromosomal translocations involving the Mixed-Lineage Leukaemia (MLL) gene underlie many human leuk...
Human probes identifying the cellular homologs of the v-ets gene, Hu-ets-1 and Hu-ets-2, and two pan...