Add to ORKGLocal delivery of a recombinant adenoassociated vector containing a tumour necrosis factor a antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability stud
Background The adeno-associated Virus (AAV) has many safety features that favor its use in the treat...
Objective: Inflammatory hand arthritis (IHA) results in impaired function. Local gene therapy with A...
Osteoarthritis (OA) affects over 40 million people annually. We evaluated interleukin-1 receptor ant...
Background: In the context of preclinical development, we studied the potential of intra-articular g...
Early and long-lasting protection from arthritis in tumour necrosis factor a (TNFa) transgenic mice ...
International audienceIntroductionProof of concept for local gene therapy for the treatment of arthr...
Toward the treatment of osteoarthritis (OA), the authors have been investigating self-complementary ...
The success of anti-tumour necrosis factor (TNF) treatment, either using antibodies or soluble recep...
With the long-term goal of developing a gene-based treatment for osteoarthritis (OA), we performed s...
This article is published under license to BioMed Central Ltd. This is an open access article distri...
Interleukin-1 (IL-1) plays an important role in the pathophysiology of osteoarthritis (OA), and gene...
The success of anti-tumour necrosis factor (TNF) treatment, either using antibodies or soluble recep...
Background Rheumatoid arthritis (RA) is a chronic autoimmune diseasethat causes inflammation and des...
Active immunization, or vaccination, with tumor necrosis factor (TNF)-Kinoid (TNF-K) is a novel appr...
Background: The adeno-associated virus (AAV) has many safety features that favor its use in the trea...
Background The adeno-associated Virus (AAV) has many safety features that favor its use in the treat...
Objective: Inflammatory hand arthritis (IHA) results in impaired function. Local gene therapy with A...
Osteoarthritis (OA) affects over 40 million people annually. We evaluated interleukin-1 receptor ant...
Background: In the context of preclinical development, we studied the potential of intra-articular g...
Early and long-lasting protection from arthritis in tumour necrosis factor a (TNFa) transgenic mice ...
International audienceIntroductionProof of concept for local gene therapy for the treatment of arthr...
Toward the treatment of osteoarthritis (OA), the authors have been investigating self-complementary ...
The success of anti-tumour necrosis factor (TNF) treatment, either using antibodies or soluble recep...
With the long-term goal of developing a gene-based treatment for osteoarthritis (OA), we performed s...
This article is published under license to BioMed Central Ltd. This is an open access article distri...
Interleukin-1 (IL-1) plays an important role in the pathophysiology of osteoarthritis (OA), and gene...
The success of anti-tumour necrosis factor (TNF) treatment, either using antibodies or soluble recep...
Background Rheumatoid arthritis (RA) is a chronic autoimmune diseasethat causes inflammation and des...
Active immunization, or vaccination, with tumor necrosis factor (TNF)-Kinoid (TNF-K) is a novel appr...
Background: The adeno-associated virus (AAV) has many safety features that favor its use in the trea...
Background The adeno-associated Virus (AAV) has many safety features that favor its use in the treat...
Objective: Inflammatory hand arthritis (IHA) results in impaired function. Local gene therapy with A...
Osteoarthritis (OA) affects over 40 million people annually. We evaluated interleukin-1 receptor ant...