Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injur
BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous sti...
AbstractAdamant progression of chronic cholangiopathies towards cirrhosis and limited therapeutic op...
Abstract Background Cirrhosis is a major health problem worldwide and new therapies are needed. Hepa...
Background/Aim: Hepatic stellate cells (HSCs) express α-smooth muscle actin (αSMA) and acquire a pro...
Insulin and insulin-like growth factor (IGF-1) are mitogenic for fibroblasts and smooth muscle cells...
Weinvestigated whether gene transfer of insulin-like growth factor I (IGF-I) to the hepatic tissue w...
We have previously shown that the administration of low doses of insulin-like growth factor-I (IGF-I...
<p><b>Number of alpha-SMA positive cells (activated HSCs) expressing IGF-I (A) and IGF-IR (B) in the...
Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apopt...
Hepatic stellate cells (HSC) play a pivotal role in hepatic tissue repair and fibrogenesis. IGF-I ha...
Liver fibrosis is characterized by the accumulation of excessive amounts of scar tissue in response ...
<div><p>Background and aims</p><p>Nonalcoholic fatty liver disease is one of the major complications...
Hepatocyte differentiation, proliferation, and apoptosis are affected by growth factors produced in ...
Background: Activated hepatic stellate cells (HSC) are central to the pathogenesis of liver fibrosis...
BACKGROUND AND AIMS:Nonalcoholic fatty liver disease is one of the major complications of obesity, o...
BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous sti...
AbstractAdamant progression of chronic cholangiopathies towards cirrhosis and limited therapeutic op...
Abstract Background Cirrhosis is a major health problem worldwide and new therapies are needed. Hepa...
Background/Aim: Hepatic stellate cells (HSCs) express α-smooth muscle actin (αSMA) and acquire a pro...
Insulin and insulin-like growth factor (IGF-1) are mitogenic for fibroblasts and smooth muscle cells...
Weinvestigated whether gene transfer of insulin-like growth factor I (IGF-I) to the hepatic tissue w...
We have previously shown that the administration of low doses of insulin-like growth factor-I (IGF-I...
<p><b>Number of alpha-SMA positive cells (activated HSCs) expressing IGF-I (A) and IGF-IR (B) in the...
Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apopt...
Hepatic stellate cells (HSC) play a pivotal role in hepatic tissue repair and fibrogenesis. IGF-I ha...
Liver fibrosis is characterized by the accumulation of excessive amounts of scar tissue in response ...
<div><p>Background and aims</p><p>Nonalcoholic fatty liver disease is one of the major complications...
Hepatocyte differentiation, proliferation, and apoptosis are affected by growth factors produced in ...
Background: Activated hepatic stellate cells (HSC) are central to the pathogenesis of liver fibrosis...
BACKGROUND AND AIMS:Nonalcoholic fatty liver disease is one of the major complications of obesity, o...
BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous sti...
AbstractAdamant progression of chronic cholangiopathies towards cirrhosis and limited therapeutic op...
Abstract Background Cirrhosis is a major health problem worldwide and new therapies are needed. Hepa...