ABBREVIATIONS: Ago, doSe of agonist required to produce 50 % mean analgesia; CI, confidence interval; DPDPE, [D-Pen25]enkephalin; EKC, ethylketocyclazocine; icy., intracerebroventricular; it., intrathecal; U50, trans±3,4hloro-N-methyI-N-[(2-pyrroIidinyl)cydohexyI]-benzeneace
The icv injection of morphine or DADLE ED50 a few min before the alkylating agent beta-FNA resulted ...
Pain encompasses both a sensory as well as an affective dimension and these are differentially proce...
This study evaluated the antinociceptive effects of systemically administered selective opioid agoni...
ABSTRACT ABBREVIATIONS: Ago, doSe of agonist required to produce 50% mean analgesia; CI, confidence ...
This study explored the antinociceptive properties of (±)-4-[(a- nociceptive effects when given by t...
Opioid analgesia is influenced by many factors, including the 1 receptor system. Current studies sho...
Some analgesics, including opioids, mediate their action through inhibitory G-protein-coupled recept...
The mu opioid receptors are unquestionably implicated both in supraspinal and spinal analgesia, but ...
Background and purposeThe opioid receptor family comprises four structurally homologous but function...
We previously described a novel cyclic endomorphin-1 analog c[Tyr-D-Pro-D-Trp-Phe-Gly] (c[YpwFG]), a...
Opioids produce myriad effects, perhaps the most clinically relevant of which is the relief of pain....
Background: Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety an...
The possibility that the opioid [delta]-receptor mediates antinociception in tests where heat is the...
The lower efficacy of opioids in neuropathic pain may be due to the increased activity of pronocicep...
Although the mu selective agonist [D-Ala2-MePhe4-Gly-ol5]enkephalin (DAMGO) and the delta selective ...
The icv injection of morphine or DADLE ED50 a few min before the alkylating agent beta-FNA resulted ...
Pain encompasses both a sensory as well as an affective dimension and these are differentially proce...
This study evaluated the antinociceptive effects of systemically administered selective opioid agoni...
ABSTRACT ABBREVIATIONS: Ago, doSe of agonist required to produce 50% mean analgesia; CI, confidence ...
This study explored the antinociceptive properties of (±)-4-[(a- nociceptive effects when given by t...
Opioid analgesia is influenced by many factors, including the 1 receptor system. Current studies sho...
Some analgesics, including opioids, mediate their action through inhibitory G-protein-coupled recept...
The mu opioid receptors are unquestionably implicated both in supraspinal and spinal analgesia, but ...
Background and purposeThe opioid receptor family comprises four structurally homologous but function...
We previously described a novel cyclic endomorphin-1 analog c[Tyr-D-Pro-D-Trp-Phe-Gly] (c[YpwFG]), a...
Opioids produce myriad effects, perhaps the most clinically relevant of which is the relief of pain....
Background: Mice lacking the preproenkephalin (ppENK) gene are hyperalgesic and show more anxiety an...
The possibility that the opioid [delta]-receptor mediates antinociception in tests where heat is the...
The lower efficacy of opioids in neuropathic pain may be due to the increased activity of pronocicep...
Although the mu selective agonist [D-Ala2-MePhe4-Gly-ol5]enkephalin (DAMGO) and the delta selective ...
The icv injection of morphine or DADLE ED50 a few min before the alkylating agent beta-FNA resulted ...
Pain encompasses both a sensory as well as an affective dimension and these are differentially proce...
This study evaluated the antinociceptive effects of systemically administered selective opioid agoni...