T IC LEPostnatal Changes in Ghrelin, Adiponectin, Insulin and Leptin Concentrations in Term Newborns

irth denotes a sharp transition from constant placental nutrient delivery to independent regulation of energy in-take and expenditure. Adiponectin, ghrelin, insulin and leptin are key hormones regulating appetite and energy ho-meostasis and could therefore be crucial compo-nents of postnatal adaptation. We studied the changes and relationships in these hormones and their correlation to clinical variables during adaptation to extrauterine life. Materials and Methods: Plasma venous adipo-nectin, ghrelin, insulin and leptin concentrations were measured at birth and controlled during early postnatal days (59.4+15.4 [SD] h, range 36