Journal of Neurology, Neurosurgery, and Psychiatry 1985;48:390-391 Matters arising Successful treatment of refactory

Sydenham's chorea with pimozide Sir: We read with interest the paper The treatment ofsevere dystonia in children and adults by Marsden et al. We describe the successful use of pimozide in a case of refractory Sydenham's chorea. The patient was a 14-year-old right-handed boy admitted to hospital for review. He presented two years earlier with right-sided hemichoreiform movements and facial grimacing which had persisted. He had a normal birth with normal motor milestones, and had had all the normal childhood illnesses including measles. There was no family history of chorea. H