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Manufactured nanoparticles are now present in many daily use commercial products such as cosmetics, paints, food packaging, etc. One of the main consequences regarding the environment is their uncontrolled release and diffusion in the aquatic systems. To explore their environmental behavior in term of stability, coagulation and dissociation, it is important to perform investigation at the laboratory scale as a prerequisite for understanding their environmental behaviors. In this study, the stability of titanium dioxide (TiO2 nanoparticles as a function of pH and fulvic acid concentration (one of the major organic component found in aquatic systems) is systematically examined by measuring the size and zeta potential variations of TiO2 nanoparticles, fulvic acids mixtures and aggregates they can form. Experiments are also conducted at three different pH values corresponding to the three possible TiO2 surface charge states: positive, neutral, and negative. The TiO2 size and zeta potential evolution is then examined as a function of the concentration of negatively charged fulvic acids (FAs) by increasing successively the [...] PALOMINO, Daniel, et al. Stability of TiO