Add to ORKGA textbook for every neurologist Neurologic paraneoplastic syndromes (NPSs) account for a tiny percentage of the complications seen in cancer patients, but they were the starting point for the interest of neurology in a discipline that would later be dubbed neuro-oncology. The possi-bility that not all neurologic lesions seen in cancer patients are due to metastases was first considered by Heinrich Oppenheim in 1888. However, the concept of the remote effect of cancer on the nervous system was first articulated by Derek Denny-Brown, when, in 1948, he reported two patients with lung carcinoma and sensory neuronopathy. The pioneers who further developed this field were mainly British neurologists: Peter Croft, Ronald Henson and Marcia Wilkins...
