Thirty patients undergoing major abdominal gynaecological surgery were anaesthetized with a standard technique including nitrous oxide in oxygen and myoneural blockade. The lungs were ventilated with large tidal volumes (10 ml kg"1) but i-'aco, remained within normal limits. Fentanyl was given as a loading dose of 10 |xg kg"1 or 25 (xg kg"1 i.v. at the start of the anaesthetic. The lower dose was followed by either an infusion of fentanyl 2 ng min"1 or by fentanyl given as increments of 100 (ig after 30 min and 50 (ig after 1 h. Significant (2 % level) second peaks of plasma fentanyl (increases greater than 0.49 ng ml"1) occurred within 45 min of the end of surgery in 60 % of patients receiving the infusion, in...
Our study was a prospective randomised study including 60 patients undergoing elective surgeries und...
Abstract: In this randomized, double-blinded study, the preemptive effects of intravenous and epidur...
BACKGROUND Postoperative nausea and/or vomiting (PONV) is one of the anaesthesia-related effects mo...
Study Objectives: To evaluate the influence of the route of administration [eppidural, intravenous (...
Adams, A. P. (1979). Plasma fentanyl concentrations and clinical observations during and after opera...
The effects of a continuous epidural administration of fentanyl on pain and on ventilation were stud...
We aimed to study the influence of prolonged administration of fentanyl on postoperative pain, intra...
We hypothesized that intrathecal fentanyl infusion would provide excellent analgesia, require lower ...
The aim of the study was to determine the accuracy of the delivery and the availability of maintaini...
We have measured haemodynamic changes and plasma concentrations of catecholamines during sufentanil-...
The effect of high-dose fentanyl anaesthesia (75ugkg~') on the metabolic and endocrine response...
Introduction: Pharmacokinetics and adverse effects are important factors in opioid investigation. Re...
Two groups of six patients were studied during light general anaesthesia using 2 % enflurane and 66 ...
The cardiovascular effects of alfentanil and fentanyl were measured during an i.v. anaesthesia techn...
Introduction. Total intravenous anaesthesia (TIVA) is induced by the pharmacodynamic interaction bet...
Our study was a prospective randomised study including 60 patients undergoing elective surgeries und...
Abstract: In this randomized, double-blinded study, the preemptive effects of intravenous and epidur...
BACKGROUND Postoperative nausea and/or vomiting (PONV) is one of the anaesthesia-related effects mo...
Study Objectives: To evaluate the influence of the route of administration [eppidural, intravenous (...
Adams, A. P. (1979). Plasma fentanyl concentrations and clinical observations during and after opera...
The effects of a continuous epidural administration of fentanyl on pain and on ventilation were stud...
We aimed to study the influence of prolonged administration of fentanyl on postoperative pain, intra...
We hypothesized that intrathecal fentanyl infusion would provide excellent analgesia, require lower ...
The aim of the study was to determine the accuracy of the delivery and the availability of maintaini...
We have measured haemodynamic changes and plasma concentrations of catecholamines during sufentanil-...
The effect of high-dose fentanyl anaesthesia (75ugkg~') on the metabolic and endocrine response...
Introduction: Pharmacokinetics and adverse effects are important factors in opioid investigation. Re...
Two groups of six patients were studied during light general anaesthesia using 2 % enflurane and 66 ...
The cardiovascular effects of alfentanil and fentanyl were measured during an i.v. anaesthesia techn...
Introduction. Total intravenous anaesthesia (TIVA) is induced by the pharmacodynamic interaction bet...
Our study was a prospective randomised study including 60 patients undergoing elective surgeries und...
Abstract: In this randomized, double-blinded study, the preemptive effects of intravenous and epidur...
BACKGROUND Postoperative nausea and/or vomiting (PONV) is one of the anaesthesia-related effects mo...