with airway inflammation in asthma than PC20 methacholine. Am J Respir Crit Care Med 2001; 163: 1546–1550. 4 Louis R, Sele J, Henket M, et al. Sputum eosinophil count in a large population of patients with mild to moderate steroid-naive asthma: distribution and relationship with methacholine bronchial hyperresponsiveness. Allergy 2002; 57: 907–912. 5 Kulkarni NS, Hollins F, Sutcliffe A, et al. Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma. J Allergy Clin Immunol 2010; 126: 61–69. 6 Pavord ID, Brightling CE, Woltmann G, et al. Non-eosinophilic corticosteroid unresponsive asthma. Lancet 1999; 353: 2213–2214. 7 Green RH, Brightling CE, Woltmann G, et al. Analysis of induced spu...
Background It is noteworthy that there is a clear clinical, epidemiological and pathophysiological a...
Abstract In asthma, the acute increment of airway responsiveness caused by exposure to allergen is a...
peer reviewedDifficult asthma is a heterogeneous disease of the airways including various types of b...
peer reviewedBACKGROUND: Although airway eosinophilia is seen as a cardinal feature of asthma, data ...
ABSTRACT: Despite full effective treatment, asthmatic patients often present with poorly controlled ...
BACKGROUND: Noneosinophilic asthma is common across asthma severities. However, in patients with mod...
BACKGROUND: Airway inflammation, acknowledged as an important feature of asthma, can be assessed by ...
In order to investigate the relationship between airways inflammation and disease severity, and impr...
Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sp...
The concept of asthma inflammatory phenotypes has proved to be important in predicting response to i...
BACKGROUND: Sputum eosinophil counts and eosinophil cationic protein (ECP) levels are usually increa...
Background: The assessment of eosinophilic airway inflammation using induced sputum identifies a cor...
peer reviewedAsthma is a complex chronic inflammatory disease of the airways. Eosinophilia is a reco...
BACKGROUND: The debate as to whether asthma is a single or heterogeneous disease remains unresolved ...
ABSTRACT: BACKGROUND: Phenotyping asthma according to airway inflammation allows identification of r...
Background It is noteworthy that there is a clear clinical, epidemiological and pathophysiological a...
Abstract In asthma, the acute increment of airway responsiveness caused by exposure to allergen is a...
peer reviewedDifficult asthma is a heterogeneous disease of the airways including various types of b...
peer reviewedBACKGROUND: Although airway eosinophilia is seen as a cardinal feature of asthma, data ...
ABSTRACT: Despite full effective treatment, asthmatic patients often present with poorly controlled ...
BACKGROUND: Noneosinophilic asthma is common across asthma severities. However, in patients with mod...
BACKGROUND: Airway inflammation, acknowledged as an important feature of asthma, can be assessed by ...
In order to investigate the relationship between airways inflammation and disease severity, and impr...
Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sp...
The concept of asthma inflammatory phenotypes has proved to be important in predicting response to i...
BACKGROUND: Sputum eosinophil counts and eosinophil cationic protein (ECP) levels are usually increa...
Background: The assessment of eosinophilic airway inflammation using induced sputum identifies a cor...
peer reviewedAsthma is a complex chronic inflammatory disease of the airways. Eosinophilia is a reco...
BACKGROUND: The debate as to whether asthma is a single or heterogeneous disease remains unresolved ...
ABSTRACT: BACKGROUND: Phenotyping asthma according to airway inflammation allows identification of r...
Background It is noteworthy that there is a clear clinical, epidemiological and pathophysiological a...
Abstract In asthma, the acute increment of airway responsiveness caused by exposure to allergen is a...
peer reviewedDifficult asthma is a heterogeneous disease of the airways including various types of b...