Urinary bladder cancer Trends Incidence Mortality

Context: Previous studies have reported substantial worldwide regional variations in bladder cancer (BCa) incidence and mortality. Objective: To describe contemporary international variations in BCa incidence and mortality rates and trends using the most recent data from the International Agency for Research on Cancer (IARC). Evidence acquisition: Estimated 2008 BCa incidence and mortality rates for each country by sex were obtained from GLOBOCAN. Recent trends in incidence for 43 countries and in mortality for 64 countries were assessed by join-point model using data from the IARC’s Cancer Incidence in Five Continents and from the World Health Organisation’s mortality database, respectively. Evidence synthesis: The highest incidence rates for both men and women are found in Europe, the United States, and Egypt, and the lowest rates are found in sub-Saharan Africa, Asia, and South America. Mortality rates are highest in parts of Europe and Slovenia, and Cuba). Among women, mortality rates decreased in 24 countries, * Corresponding authorremained stable in 36 countries, and increased in 5 countries (central and eastern Europe). Conclusions: Incidence and mortality rates in general decreased in most Western countries but increased in some eastern European and developing countries. These patterns in part may reflect differences in the stage and extent of the tobacco epidemic, changes in coding practices, prevalence of schistosomiasis (Africa), and occupational exposure