Purpose: To demonstrate the use of American Society of Clinical Oncology (ASCO) Quality Oncology Practice Initiative

(QOPI) measures as part of a financial incentive plan for an aca-demic health center–based hematology-oncology division. Methods: An 11-member QOPI-certified hematology-oncology division participated in a pilot variable compensation (VC) plan with group-specific targets selected based on prior below-aver-age performance. Twenty percent of overall VC was linked to success in two QOPI categories: completion of treatment sum-maries within 90 days of end of chemotherapy and assessment of patients ’ emotional well-being by second office visit. Three tiers of achievement were set for each goal. A formula combining VC goals into year-end payout was driven by three levels of percent base salary: 8%, 12%, and 24%, with probability of achievement of each goal of 90%, 50%, and 10%, respectively. Practice leadership was educated about QOPI acceptance in the oncology community. Results: The division participated in QOPI during spring and fall 2012. With systems-based improvements, 40.54 % of medi-cal records audited had treatment summaries, resulting in achievement of tier III compensation. Documentation of emo-tional well-being increased, yielding 63 % of patient cases com-pliant; however, the national benchmark concurrently improved, making this insufficient to achieve tier I. Conclusion: QOPI metrics can be used as a quality incentive for oncologists in a VC plan. Nononcologists can appreciate the strength of QOPI as a quality tool. The combination of a QOPI program through ASCO and use of various QOPI metrics can drive continuous improvement in an oncology group