Add to ORKGAdult male-8prague-Dawley rats were exposed to manganese for a period of eight months by giving them drinking water containing 0.1, 1.0 and 5.0 mg Mn/ml, as MnCI2. This experimental animal model for chronic manganese poisoning shares neuropathological features with the human disease such as cortical and striatal alteratioDS. Our results suggest that relatively low con centratioDS of manganese (1.0 molml) orally ingested are capable of inducing morphological alterations as evidenced by light microscopy studies
The adequacy of existing animal studies to understand the effects of chronic low-level manganese exp...
Manganese (Mn) is both an essential nutrient and a toxicant, with speciWc eVects on liver and kidney...
The toxicokinetics of manganese (Mn) was investigated in male and female rats either following a sin...
Manganese (Mn) is the twelveth most abundant element on the earth. It is an essential trace metal th...
Background: The relation of man with manganese-exposing jobs may cause manganism, a Parkinson-like d...
In the present study we have characterized a rat model of manganese (Mn) intoxication leading to beh...
Background: Manganese, an essential micronutrient, is a potential neurotoxicant in prolonged overe...
Prolonged exposure to manganese in mammals may cause an extrapyramidal disorder characterized by dys...
Manganese is an essential trace element required for normal development and bodily functions. Howeve...
Chronic exposure to manganese (Mn) is known to produce a parkinsonian or dystonic state in humans ca...
Manganese (Mn) is an essential metal for development and metabolism. However, exposures to high Mn l...
Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in ...
Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in ...
Manganese (Mn) is a naturally occurring element and an essential nutrient for humans and animals. Ho...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The adequacy of existing animal studies to understand the effects of chronic low-level manganese exp...
Manganese (Mn) is both an essential nutrient and a toxicant, with speciWc eVects on liver and kidney...
The toxicokinetics of manganese (Mn) was investigated in male and female rats either following a sin...
Manganese (Mn) is the twelveth most abundant element on the earth. It is an essential trace metal th...
Background: The relation of man with manganese-exposing jobs may cause manganism, a Parkinson-like d...
In the present study we have characterized a rat model of manganese (Mn) intoxication leading to beh...
Background: Manganese, an essential micronutrient, is a potential neurotoxicant in prolonged overe...
Prolonged exposure to manganese in mammals may cause an extrapyramidal disorder characterized by dys...
Manganese is an essential trace element required for normal development and bodily functions. Howeve...
Chronic exposure to manganese (Mn) is known to produce a parkinsonian or dystonic state in humans ca...
Manganese (Mn) is an essential metal for development and metabolism. However, exposures to high Mn l...
Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in ...
Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in ...
Manganese (Mn) is a naturally occurring element and an essential nutrient for humans and animals. Ho...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The adequacy of existing animal studies to understand the effects of chronic low-level manganese exp...
Manganese (Mn) is both an essential nutrient and a toxicant, with speciWc eVects on liver and kidney...
The toxicokinetics of manganese (Mn) was investigated in male and female rats either following a sin...