Obesity as an adverse prognostic factor for patients receiving adjuvant chemotherapy for breast

• Objective: To determine whether obesity is an inde-pendent prognostic factor among women receiving adjuvant chemotherapy for lymph node-positive breast cancer and to determine how obesity relates to other commonly used prognostic indicators. • Design: Retrospective review of the clinical charac-teristics and clinical course of 735 patients with stages II and III primary breast cancer who were treated using three consecutive postoperative adjuvant chemother-apy protocols. Univariate and multivariate analyses were used to determine the prognostic implications of obesity defined by weight and height tables and body mass index. In addition, we analyzed the relation be-tween obesity and other known prognostic indicators for patients with primary breast cancer