NEUROCYSTICERCOSIS AND MICROSCOPIC HIPPOCAMPAL DYSPLASIA IN A PATIENT WITH REFRACTORY MESIAL TEMPORAL LOBE EPILEPSY

ABSTRACT- Epidemiologic studies suggest that neuro c y s t i c e rcosis (NC) is the main cause of symptomatic epilepsy in developing countries. The association between NC and mesial temporal lobe epilepsy (MTLE) has been re p o rted by several authors. Recent data have shown that the presence of NC does not influence the clinical and pathological profile in MTLE patients and suggest that not all cysticercotic lesions are ine-vitably epileptogenic. We describe a 50-years-old woman with partial seizures due to NC which evolve to MTLE. The patient was submitted to a corticoamygdalohippocampectomy to treat re f r a c t o ry epilepsy. An immunohistochemical study using neuronal markers was made on hippocampal formation. Besides the typical aspects of Ammon’s horn sclerosis (AHS), the microscopic examination demonstrates cellular fea