meeting pointeeting point The Keystone Symposium on Stem Cell Differentiation and Dediffer-entiation held in February this year

Disease, UCSF). The five-day meeting kicked off with a presentation from James Thomson (Morgridge Institute, Wisconsin), a pioneer in human embryonic stem cell (ESC) deri-vation. Thomson began with what was to rapidly emerge as a recurring theme in the meeting—that human stem cells gener-ated by induced pluripotency show var-ied phenotypes that can be moderated by recloning, but probably reflect the different cellular origins of the somatic cells from which they arose. The good, bad and unpredictable Induced pluripotent stem cells (iPSCs) were elaborated originally by Kazutoshi Takahashi (Center for iPS Cell Research and Application, Kyoto U.) and Yamanak