Add to ORKGExperimental human pneumococcal carriage (EHPC) is scientifically important because nasopharyngeal carriage of Streptococcus pneumoniae is both the major source of transmission and the prerequisite of invasive disease. A model of carriage will allow accurate determination of the immunological correlates of protection, the immunizing effect of carriage and the effect of host pressure on the pathogen in the nasopharyngeal niche. Further, methods of carriage detection useful in epidemiologic studies, including vaccine studies, can be compared. Aim We aim to develop an EHPC platform that is a safe and useful reproducible method that could be used to down-select candidate novel pneumococcal vaccines with prevention of carriage as a surrogate of ...
Item does not contain fulltextThe density and duration of pneumococcal carriage are considered to af...
AbstractBackgroundPneumococcal carriage is a reservoir for transmission and a precursor to pneumococ...
Streptococcus pneumoniae is a leading cause of bacterial pneumonia, sepsis and meningi-tis. Surface ...
Experimental human pneumococcal carriage (EHPC) is scientifically important because nasopharyngeal c...
Background The pneumococcus is a diverse pathogen whose primary niche is the nasopharynx. Over 90 di...
Colonization of the human nasopharynx by pneumococcus is extremely common and is both the primary re...
BACKGROUND: Numerous studies evaluating the efficacy of conjugate pneumococcal vaccines are being co...
The burden of pneumococcal pneumonia remains high worldwide. The disease disproportionately affects ...
Introduction: Nasopharyngeal colonization is a precondition for mucosal and invasive pneumococcal di...
BackgroundPersistent carriage of pneumococcal vaccine serotypes has occurred after introduction of P...
Rationale: The immunological and protective role of pneumococcal carriage in healthy adults is not k...
INTRODUCTION: Despite widely available vaccinations, Streptococcus pneumoniae (SPN) remains a major ...
The pneumococcus is a diverse pathogen whose primary niche is the nasopharynx. Over 90 different ser...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Infections caused by Streptococcus pneumoniae are a major cause of morbidity and mortality globally:...
Item does not contain fulltextThe density and duration of pneumococcal carriage are considered to af...
AbstractBackgroundPneumococcal carriage is a reservoir for transmission and a precursor to pneumococ...
Streptococcus pneumoniae is a leading cause of bacterial pneumonia, sepsis and meningi-tis. Surface ...
Experimental human pneumococcal carriage (EHPC) is scientifically important because nasopharyngeal c...
Background The pneumococcus is a diverse pathogen whose primary niche is the nasopharynx. Over 90 di...
Colonization of the human nasopharynx by pneumococcus is extremely common and is both the primary re...
BACKGROUND: Numerous studies evaluating the efficacy of conjugate pneumococcal vaccines are being co...
The burden of pneumococcal pneumonia remains high worldwide. The disease disproportionately affects ...
Introduction: Nasopharyngeal colonization is a precondition for mucosal and invasive pneumococcal di...
BackgroundPersistent carriage of pneumococcal vaccine serotypes has occurred after introduction of P...
Rationale: The immunological and protective role of pneumococcal carriage in healthy adults is not k...
INTRODUCTION: Despite widely available vaccinations, Streptococcus pneumoniae (SPN) remains a major ...
The pneumococcus is a diverse pathogen whose primary niche is the nasopharynx. Over 90 different ser...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Infections caused by Streptococcus pneumoniae are a major cause of morbidity and mortality globally:...
Item does not contain fulltextThe density and duration of pneumococcal carriage are considered to af...
AbstractBackgroundPneumococcal carriage is a reservoir for transmission and a precursor to pneumococ...
Streptococcus pneumoniae is a leading cause of bacterial pneumonia, sepsis and meningi-tis. Surface ...