EVALUATION OF FOURTH-GENERATION IMMUNOASSAYS FOR DETECTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION

Introduction: The scr eening methods for determination of HIV infection have been deve-loped from the first-generation to the fourth-generation assays. The fourth-generation assays are the combination methods that can detect HIV-1, HIV-2 antibodies and HIV p24 antigen. In this study, we evaluate two fourth-generation assays, AxSym HIV Ag/Ab Combo (Enzyme-linked immunosorbent assay; ELISA, Abbott laboratories) and Cobas HIV Ag/Ab Combi (Electrochemi